6 Causes for peptic ulcer

6 Causes for peptic ulcer

Peptic ulcer is erosion in the inner lining of the gastric mucosa which usually occurs as a complication of chronic gastritis. Peptic ulcer develops due to many factors, such as:

  1. Helicobacter pylori.
  2. Overconsumption of non-steroidal anti-inflammatory drugs (NSAIDs).
  3. Excessive smoking.
  4. Frequent spicy food or caffeine beverages (coffee & tea).
  5. Crohn's disease.
  6. Excessive and continuous exposure to emotional stress.

The clinical picture of peptic ulcer consists of the following signs:

  • Nausea and vomiting.

  • Epigastric pain.

  • Heartburn.
  • Abdominal bloating.
  • Weight loss.
  • Loss of appetite.
  • Hematemesis or melena (or both) in advanced cases.

On the other hand, gastric perforation is the most common complication of peptic ulcer, which could lead to peritonitis and septicemia.

Most cases of peptic ulcer are diagnosed by the associated clinical picture, diagnosis can be confirmed by barium contrast X-ray or endoscopy.

Management of peptic ulcer includes the following:

  • Treatment of the cause (H. pylori, crohn's disease… etc).

  • Medication: antacids, proton pump inhibitors, anticoagulants and IV fluids.

  • Blood transfusion and fresh frozen plasma to compensate blood loss.
  • Active peptic ulcers should be managed by cauterization to stop blood loss.

 


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